Dr. Jhenny F. Galan

Dr. Galan

Texas A&M University at Galveston
Telephone No.: 409-741-4326
Email: galanj@tamug.edu

Assistant Professor

EDUCATION:

Ph.D. Chemistry, University of Connecticut, 2006
B.S. Chemistry, University of the Philippines, 1996

RESEARCH INTERESTS:

• Structure-function relationship studies of protein systems using all-atom and coarse-grain molecular dynamics simulations
• Testing and validation of coarse-grain forcefield for proteins
• Computational studies of the membrane translocation ability of heteroaromatic foldamers and its implications in drug delivery
• Understanding conformational preferences of aromatic oligoamide foldamers using theoretical methods

SPECIALTY:

Computational Chemistry, Physical Chemistry, Biophysical Chemistry

SELECTED PUBLICATIONS:

Chen, M. S., Sandberg, D. J., Babu, K. R., Bubis, J., Surya, A., Ramos, L.S., Galan, J.F., Sandberg, M., Birge, R. and Knox, B.E. Conserved residues in the extracellular loops of short-wavelength cone visual pigments, Biochemistry, 2011, 50(32), 6763-73

Galan, Jhenny F., Brown, Jodian, Wildin, Jayme L., Liu, Zhiwei, Liu, Dahui, Moyna, Guillermo, and Pophristic, Vojislava. Intramolecular Hydrogen Bonding in ortho-Substituted Arylamide Oligomers: A Computational and Experimental Study of ortho-Fluoro and ortho-Chloro N-methylbenzamides. J. Phys. Chem. B, 113(38), 12809-12815, 2009

Galan, Jhenny F., Gao, J. , Pabuwal, V. , Meek, P.J. and Li, Z. Application of Network Theory in Understanding and Predicting Protein Structure and Function. Current Proteomics, 5, 181-190, 2008

Amora, Tabitha, Ramos, Lavoisier, Galan, Jhenny F. and Birge, Robert, R. Spectral Tuning of Deep Red Cone Pigments. Biochemistry, 47(16), 4614-4620, 2008

Rangarajan, Rekha, Galan, Jhenny F., Whited, Gregg, and Birge, Robert R.   The Mechanism of Spectral Tuning of Green-Absorbing Proteorhodopsin, Biochemistry, 46 (44), 12679-12686, 2007

Hillebrecht, Jason R., Galan, Jhenny F., Rangarajan, Rekha, Ramos, Lavoisier R., McCleary, Kristina N., Ward, Donald E., Stuart, Jeffrey A. and Birge, Robert R. Structure, Function and Wavelength Selection in Blue-Absorbing Proteorhodopsin, Biochemistry, 45 ( 6 ),1579-1590, 2006

Whitmire, S.E., Wolpert, D., Markelz, A.G., Hillebrecht, J.R., Galan, J. and Birge, R. R. Protein Flexibility and Conformational State: A Comparison of Collective Vibrational Modes of Wild-Type and D96N Bacteriorhodopsin. Biophysical Journal, Vol 85, 1269-1277, 2003

Xu, Jing , Ramian, Gerry J., Galan, Jhenny F., Savvidis, Pavlos G., Scopatz, Anthony M., Birge, Robert R.  , Allen, James S., and Plaxco, Kevin W.  Terahertz Circular Dichroism Spectroscopy: A Potential Approach to the In Situ Detection of Life’s Metabolic and Genetic Machinery. Astrobiology, Vol 3, Number 3, 2003

Galan, J. et al. Conformational preferences of furan- and thiophene-based amides: A molecular dynamics and NOE study, Chemistry: A European Journal, 2012, in preparation

Galan, J. F. , Devane, R, Liu, Z., Nguyen, T. H. and Moore, P. B. A Coarse grain model for proteins: Implications in Simulation of Biomolecules, J Chem Theory Comput, 2012, in preparation

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